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ASTM E2525 Standard Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies

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ASTM International

Standard Test Method for Evaluation of the Effect of Nanoparticulate Materials on the Formation of Mouse Granulocyte-Macrophage Colonies
 N E2525

 

Annotation

 

This test method provides a protocol for quantitative analysis of the effect of nanoparticulate materials in physiologic solution on granulocyte-macrophage colony-forming units.

This test method employs murine bone marrow hematopoietic stem cells which proliferate and differentiate to form discrete cell clusters or colonies which are counted.

This test method is part of the in vitro preclinical characterization cascade for nanoparticulate materials for systemic administration in medical applications.

The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

 

Автоматический перевод:

 

Стандартный метод испытаний для оценки эффекта материалов Nanoparticulate по формированию колоний макрофага гранулоцита мыши

Этот метод испытаний обеспечивает протокол для количественного анализа эффекта nanoparticulate материалов в физиологическом растворе на единицах формирования колоний макрофага гранулоцита.

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